What is Fondaparinux?

Fondaparinux (Arixtra) is an anticoagulant injection. It prevents a clotting factor, Factor Xa, from helping the formation of clots. Thus, this medication helps “thin” your blood.

How it is administered:

This medication is most typically administered as a subcutaneous injection. In a hospital setting, it may be administered as an intravenous infusion. The medication is available as a prefilled syringe; the air bubble must not be expelled prior to administration. It is also recommended that the site of the injection be rotated to avoid irritation. 

What to expect:

Fondaparinux is an anticoagulant, thus, bleeding is the most common adverse effect. Additional side effects include low blood pressure, increased wound secretions, insomnia and confusion. A blister may develop at the injection site as well. Increased bruising may occur, especially near the site of injection.