Provenge – Sipuleucel-T

Patient Education Quick Reference Guide Diablo Valley Oncology/Hematology Medical Group Phone Number: 925-677-5041

Why is this medication prescribed? Septra is an antibiotic combination containing sulfamethoxazole and trimethoprim and it works by killing sensitive bacteria. Both ingredients are antibiotics that treat different types of infection caused by bacteria. Septra is used to treat ear infections, urinary tract infections, bronchitis, traveler’s diarrhea, and Pneumocystis carinii pneumonia. Septra may also be used for other purposes not listed in this medication guide. How should this medicine be used? Take Septra exactly as prescribed by your doctor. Do not take it in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. Take Septra for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Septra will not treat a viral infection such as the common cold or flu. Drink plenty of fluids to prevent kidney stones while you are taking trimethoprim and sulfamethoxazole. Store the tablets and liquid at room temperature away from moisture, heat, and light. What special precautions should I follow? You should not use Septra if you are allergic to sulfamethoxazole or trimethoprim, if you are pregnant or breast-feeding, or if you have anemia (lack of red blood cells) caused by folic acid deficiency. To make sure you can safely take Septra, tell your doctor if you have any of these other conditions:
  • kidney or liver disease;
  • a folic acid deficiency;
  • asthma or severe allergies;
  • AIDS;
  • a glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency); or
  • if you are malnourished.
  FDA pregnancy category C. It is not known whether Septra will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Sulfamethoxazole and trimethoprim can pass into breast milk and may harm a nursing baby. Do not use Septra without telling your doctor if you are breast-feeding a baby. Do not give Septra to a child younger than 2 months old. Older adults may be more likely to suffer side effects from this medication. What special dietary instructions should I follow? Follow your doctor’s instructions about any restrictions on food, beverages, or activity. What should I do if I forget a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What side effects can this medication cause? Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:
  • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
  • the first sign of any skin rash, no matter how mild;
  • pale skin, easy bruising or bleeding;
  • cough, feeling short of breath;
  • diarrhea that is watery or bloody;
  • feeling restless or irritable, confusion, hallucinations, seizure;
  • slow heart rate, weak pulse, severe tingling, numbness, muscle pain or weakness;
  • nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • fever, chills, body aches, flu symptoms; or
  • urinating less than usual or not at all.
  Less serious Septra side effects may include:
  • painful or swollen tongue;
  • dizziness, spinning sensation;
  • ringing in your ears;
  • joint pain; or
  • sleep problems (insomnia).
  This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 What other information should I know? You should not use Septra if you are allergic to sulfamethoxazole or trimethoprim, if you are pregnant or breast-feeding, or if you have anemia (lack of red blood cells) caused by folic acid deficiency. Before using Septra, tell your doctor if you have kidney or liver disease, a folic acid deficiency, asthma or severe allergies, AIDS, a glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency), or if you are malnourished. Take Septra for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Septra will not treat a viral infection such as the common cold or flu. Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to. Avoid exposure to sunlight, sunlamps, or tanning beds. Septra can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors . Tell your doctor about all other medications you use, especially:
  • seizure medication such as phenytoin (Dilantin);
  • a diuretic (water pill);
  • a blood thinner such as warfarin (Coumadin);
  • methotrexate (Trexall, Rheumatrex); or
  • an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).
  This list is not complete and there may be other drugs that can interact with Septra. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor. Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to. Avoid exposure to sunlight, sunlamps, or tanning beds. This medication can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.